John Lewis was born 1747. He inherited the Lewis plantation in Fredericksburg and sold the property soon after his mother's death in 1797. He eventually moved to Kentucky, where he died in 1825. He was married three times:

• Lucy Thornton (one child, Mildred Gregory, born 1770)
• Elizabeth Thornton (no children)
• Elizabeth Jones (three children)

Frances Lewis was once thought to have died young, but is now known to have lived until at least 1765, possibly as late as 1781. She might have married but there is no record of living issue.

Fielding Lewis, Jr. was born 14 February, 1750/51 in Fredericksburg, VA and died 21 July, 1803 in Spotsylvania Co., VA. He married (1) Nancy Alexander, daughter of Gerard Alexander and Mary Dent, in 1769 in Alexandria, VA. She was born 1756 in Alexandria, VA and died about 1788. He married (2) Elizabeth Dade, daughter of Townshend Dade and Parthenia Alexander, on 26 March, 1789 in Alexandria, VA. She died before 1809 in Alexandria VA. Fielding Lewis, Jr. was a planter, serving as a Captain in the military during the Revolutionary War. He had a history of being debt-ridden and was in debtor's prison in Winchester, Frederick Co., VA in 1790.

Children (by Nancy):

• Elizabeth Alexander - born 1772; died 1836
• Charles - born 1775; died 1829
• George Warner - born before 1777
• John Augustine - born about 1778
• Robert - born 1782
• Nancy - born 1787; died 1835

Children (by Elizabeth):

• Catherine Dade - born 1790; died after 1850
• Lucinda Elizabeth - born 1793

George Lewis was born 14 March, 1757 in Fredericksburg, VA and died 15 November, 1821 at Marmion, King George Co., VA. He married Catherine Daingerfield, 15 October, 1779 at Coventry, Spotsylvania Co., VA. She was born at Coventry, Spotsylvania Co., VA and died 16 February, 1820 at Marmion, King George Co., VA. George Lewis attended Princeton and worked as Aide-de-Camp for his uncle, George Washington, during the Revolutionary War. His plantation home was called Marmion.

Children:

• Samuel - born 1780
• Mary Willis - born 1782
• Daingerfield - born 1785

Betty Lewis was born 23 February, 1765 in Fredericksburg, VA and died 9 August, 1830 at Audley, Clarke Co., VA. She married Charles Carter, 7 May, 1781 in Fredericksburg, VA. He was born in 1765 at Blenheim, Albemarle Co., VA and died 1829 at Audley, Clarke Co., VA.

Children:

• Betty Washington Carter - born 1782; died 1795
• Sally Champe Carter - born 1783; died 1784
• Marie Ball Carter - 1784; died 1823
• Edward Carter - born 1786; died 1795
• Sarah Carter - born 1789; died 1807
• George Washington Carter - born 1791; died 1833
• Charles Lewis Carter - born 1792; died 1792
• Mary Willis Carter - born 1793; died 1793
• Elizabeth Washington Carter - born 1795; died 1811
• Charles Edward Carter - born 1796
• William Farley Carter - 1799; died 1862
• Eleanor Custis Lewis Carter - born 1800; died 1845
• Lawrence Fielding Carter - born 1803; died 1827
• Otway Ann Carter - born 1805
• Edward Frederick Carter - born 1807; died 1814

Lawrence Lewis was born 4 April, 1767 in Fredericksburg, VA and died 20 November, 1839 in Arlington, VA. He married Eleanor Parke Custis, 22 February, 1799 at Mount Vernon. She was born 21 March, 1779 in Abingdon, VA and died at Audley, Clarke Co., VA. Lawrence Lewis worked as Aide-de-Camp to Major General Morgan in the Whiskey rebellion of 1794 and later as personal secretary to George Washington. He worked at Mount Vernon, where he met and married Eleanor "Nellie" Custis, daughter of Martha Washington by her first marriage to Daniel Parke Custis. Until after George Washington's death, the couple lived at Mount Vernon; then they built Woodlawn on property once part of Mount Vernon.

Children:

• Frances Parke - born 1799; died 1875
• Martha Betty - born 1801; died 1802
• Lawrence Fielding - born 1802; died 1802
• Lorenzo - born 1803; died 1847
• Eleanor Agnes Freire - born 1805; died 1820
• Fielding Augustine - born 1807; died 1809
• George Washington Custis - born 1810; died 1811
• Martha Eleanor Angela - born 1813; died 1878

Robert Lewis was born 25 February, 1769 in Fredericksburg, VA and died 16 January, 1829 at Lansdowne, Fredericksburg, VA. He married Judith Carter Browne after 1791 at Elsing Green, King William Co., VA. She was born 10 December, 1773 at Elsing Green, King William Co., VA and died 29 November, 1830 at Lansdowne, Fredericksburg, VA. Robert Lewis acted as private secretary to George Washington, married and lived in Spotsylvania County. He served as mayor of Fredericksburg for two terms. As Mayor, he gave the welcoming speech when Lafayette visited Fredericksburg in 1824.

Children:

• Judith Carter - born 1794
• Betty Burnett - born 1808

Howell Lewis was born in 1771 and died in 1822. He rented a farm in Frederick Co., VA. He acted as personal secretary to George Washington after his brother Robert. He later managed Mount Vernon. Howell moved to Kanawha Co., WV to property he inherited from George Washington. He was married one time to Ellen Hackley Pollard. They had 11 children.